How can you enable or disable Desktop Cleanup Wizard?

You must make the following changes to the Windows registry.

CAUTION: We strongly recommend that you back up the registry before you make any changes to it. Incorrect changes to the registry can result in permanent data loss or corrupted files. Modify only the keys that are specified. Read the document How to make a backup of the Windows registry for instructions.

Parlandosparlando strongly recommends that you back up the registry before making any changes to it.
Incorrect changes to the registry can result in permanent data loss or corrupted files. Modify the specified subkeys only.
Read the document: How to make a backup of the Windows registry.

Click on START > RUN and type regedit
Then click on Ok button.

The Registry Editor, will be appeared.
In the left pane of the Registry Editor, navigate to the following subkey (making double click on each registry key):

HKEY_CURRENT_USER
Software
Microsoft
Windows
CurrentVersion
Explorer
Desktop
CleanupWiz

Now, in the right pane of the Registry Editor locate and make double click on the following registry subkey named NoRun.

If not, make it. For this case, in the right pane of the Registry Editor, right click in the white space and choose NEW > DWORD Value to create a new subkey.
Name it NoRun
Now, make double click on it.

A new window will be appeared.
Modify the value in the field named Value data

Set the value for this subkey to:
0 (read ZERO) to enable wizard;
1 (read ONE) to disable wizard.

Then click on Ok button.

Exit the Registry Editor.

Restart the computer.